How is escitalopram metabolised?

Escitalopram is metabolised by the cytochrome P450 enzymes, CYP3A4, 2C19 and 2D6, to its main metabolite, demethyl escitalopram. The latter is further metabolised to didemethyl escitalopram, and this seems to be partly catalysed by CYP2D6. Other metabolites are a propionic acid derivative, N-oxide metabolite and glucuronides.