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Q & A

Are there other antidepressants that are present as pure enantiomers?

Of the presently available antidepressants that exist as stereoisomers, some have been introduced as racemates and some as single enantiomers.

Drug class	Chiral drug	Introduced as:
TCA	Mianserin	racemate
TCA	Trimipramine	racemate
SSRI	Citalopram	racemate
	Fluoxetine	racemate
	Paroxetine	enantiomer
	Sertraline	enantiomer
NaSSA	Mirtazapine	racemate
SNRI	Venlafaxine	racemate
SNRI	Milnacipran	racemate
NARI	Reboxetine	racemate

Published: 29/09/2006 Last updated: 27/07/2010

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