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Unique Serotonin Dual-Action

The pharmacology of citalopram enantiomers: the antagonism by R-citalopram on the effect of s-citalopram

Sanchez C, Basic Clin Pharmacol Toxicol. 2006 Aug;99(2):91-5

The S-enantiomer of R,S-citalopram, increases inhibitor binding to the human serotonin transporter by an allosteric mechanism. Comparison with other serotonin transporter inhibitors.

Chen et al., Eur Neuropsychopharmacol. 2005 Mar;15(2):193-8.

Escitalopram versus citalopram: the surprising role of the R-enantiomer

Sanchez et al., Psychopharmacology 2004; 174: 163-176

R-Citalopram functionally antagonises Escitalopram in vivo and in vitro: evidence for kinetic interaction at the Serotonin transporter

Stórustovu et al., British Journal of Pharmacology 2004; 142: 172-180

Last updated: 23.05.2006

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