Efficacy in panic disorder (PD)

Change in panic attacks frequency from baseline (log transformed) (ref.1) * Significantly different from placebo, p=<0.05

• In a 10-week trial, escitalopram (10–20 mg/day) significantly reduced the frequency of panic attacks compared with placebo.

Mean change from baseline P&A scale total score (ref.1) * Significantly different from placebo, p=<0.05 ** Significantly different from placebo , p=<0.01

• Escitalopram significantly improved CGI ratings for panic attacks, anticipatory anxiety and phobic avoidance compared with placebo
• Significantly more escitalopram-treated patients achieved remission compared with placebo-treated patients.

References:

1. Stahl et al., 2003