Cipralex vs. Paroxetine (GAD)

Adjusted mean change from baseline in HAM-A total score (ref.1) * Significantly different from placebo p<0.05 ** Significantly different from placebo p<0.01 ***Significantly different from placebo p<0.001 #Significantly different from paroxetine p<0.05

• Escitalopram (10 mg/day) was statistically superior to paroxetine 20 mg/day in the treatment of GAD after 12 weeks.

Mean DESS total score (ref.1) *** Significantly different from placebo, p<0.001

• On discontinuation of treatment, significantly more discontinuation-emergent symptoms were recorded for paroxetine.

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References:

1. Baldwin et al., 2004