Cipralex vs. Venlafaxine XR
Cipralex (escitalopram) compares favourably to venlafaxine, both in moderate and severely ill depressed patients.
Mean change from baseline in MADRS total score (ref.1) *significantly different from venlafaxine xr, p<0.05 |
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The results of two studies demonstrated that escitalopram is at least as effective and better tolerated than venlafaxine XR. (
ref.1)
Patients in sustained remission (%) (ref.2) |
As % of patients in remission at week 8 (ref.2) ANCOVA, p<0.001 |
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More severely ill patients reach sustained remission when treated with Cipralex (escitalopram) 20 mg compared to venlafaxine up to 225mg. The excellent tolerability of Cipralex is an extra benefit when compared to venlafaxine. (
ref.2)
References:
1. Montgomery et al., 2006
2. Montgomery et al., 2004