Cipralex vs. venlafaxine XR

Mean change from baseline in MADRS total score (ref.1) *significantly different from venlafaxine xr, p<0.05

• The results of two studies demonstrated that escitalopram is at least as effective and better tolerated than venlafaxine XR. (ref.1)

Patients in sustained remission (%) (ref.2)

As % of patients in remission at week 8 (ref.2) ANCOVA, p<0.001

• More severely ill patients reach sustained remission when treated with Cipralex (escitalopram) 20 mg compared to venlafaxine up to 225mg. Cipralex has the additional advantage of having a comparatively better tolerability profile than venlafaxine (ref.2)

References:

1. Montgomery et al., 2006

2. Montgomery et al., 2004