Cipralex vs. Placebo
Cipralex presents better efficacy and faster symptom relief
Mean change in MARDS score (ref.1)![Mean change from baseline in MADRS total score in patients with major depressive disorder treated with escitalopram 10 mg/day, escitalopram 20 mg/day, citalopram 40 mg/day or placebo (last observation carried forward [LOCF] analysis) during an 8-week period.](/content/pictures/about/efficacy/jpeg/figure15.jpg) * Significantly different from placebo, p<0.05
** Significantly different from placebo, p<0.01
Asterisks at weeks 2,4 and 6 refer to p-values for escitalopram 10 and 20 mg/day |
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Studies have demonstrated the robust and consistent efficacy of escitalopram. A significant difference was observed between treatment with escitalopram and placebo in the primary outcome variable (MADRS total score at week 8, LOCF) in five out of six studies. (
ref.1)
Change in CGI-S score (ref.2) |
CGI-I score (ref.2) * Significantly different from placebo, p<0.05
** Significantly different from placebo, p<0.01 |
References:
1. Burke et al., 2002
2. Lepola et al., 2003