Cipralex vs. citalopram

MADRS total score, mean change from baseline (ITT) (ref.1) * p< 0.05 vs. placebo ** p< 0.01 vs. placebo # p< 0.05 vs. citalopram ## p< 0.01 vs. citalopram

• Superior efficacy compared with citalopram has been shown in individual studies, pooled- and meta-analyses. Escitalopram 10–20 mg/day was more efficacious than citalopram 20–40 mg/day in reducing the symptoms of depression and provided more rapid relief. The observed differences were particularly pronounced in severely ill patients.

Percentage of patients (ref.2) # Significantly different from citalopram, p<0.05

• Clinical studies have consistently shown superior response and remission rates with Cipralex vs. citalopram.

References:

1. Llorca et al. Int J Clin Pract 2005;59:268-75

2. Lepola et al. Int Clin Psychopharmacol 2003;18(4):211-7