Cipralex vs. citalopram

MADRS mean change from baseline (ref.1) * p≤0.05 vs. placebo ** p≤0.01 vs. placebo *** p≤0.001 vs. placebo #≤0.05 vs. citalopram

• Early onset of symptom improvement may increase patient adherence to treatment and reduce progression in major depression. (ref.1)
• Cipralex significantly improved depressive symptoms from week 1 compared to placebo and citalopram

Mean change in MADRS score (ref.2) *Significantly different from placebo, p<0.05 ***Significantly different from placebo, p<0.001 #Significantly different from citalopram, p<0.05

• Severely ill Cipralex patients (MADRS >=30) showed greater improvement than citalopram patients (ref.2)

References:

1. Lepola et al. Int Clin Psychopharmacol 2004;19:149-55

2. Gorman et al. 2002